Cathepsin inhibitor 1
(S)-3-(tert-butyl)-N-(3-(3-chlorophenyl)-1-((cyanomethyl)amino)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide
CAS: 225120-65-0
Molecular Formula: C20H24ClN5O2
Cathepsin inhibitor 1 - Names and Identifiers
Cathepsin inhibitor 1 - Physico-chemical Properties
| Molecular Formula | C20H24ClN5O2 |
| Molar Mass | 401.89 |
| Storage Condition | -20℃ |
| Use | Cathepsin inhibitor 1 (Compound 25) is a potent and selective Cathepsin inhibitor with pIC50 values of 7.9,6.7,6.0,5.5 and 5.2 for inhibiting CatL,CatL2,CatS,CatK and CatB, respectively. |
Cathepsin inhibitor 1 - Reference
| Reference Show more | 1: Coers J, Ranft C, Skoda RC. A truncated isoform of c-Mpl with an essential C-terminal peptide targets the full-length receptor for degradation. J Biol Chem. 2004 Aug 27;279(35):36397-404. Epub 2004 Jun 21. PubMed PMID: 15210714. 2: Zhu DM, Uckun FM. Cathepsin inhibition induces apoptotic death in human leukemia and lymphoma cells. Leuk Lymphoma. 2000 Oct;39(3-4):343-54. PubMed PMID: 11342315. |
Cathepsin inhibitor 1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.488 ml | 12.441 ml | 24.882 ml |
| 5 mM | 0.498 ml | 2.488 ml | 4.976 ml |
| 10 mM | 0.249 ml | 1.244 ml | 2.488 ml |
| 5 mM | 0.05 ml | 0.249 ml | 0.498 ml |
Last Update：2024-01-02 23:10:35
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View History
Cathepsin inhibitor 1
Methyl 4-azaspiro[2.5]octane-7-carboxylate
9006-03-5
3-三氟甲基-4-甲基溴苯
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4-氨基苯甲脒二盐酸盐
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6 - 氨甲基-4H-苯并[1,4]恶嗪-3 - 酮盐酸盐
Methyl 4-azaspiro[2.5]octane-7-carboxylate
9006-03-5
3-三氟甲基-4-甲基溴苯
Pentaerythritrol polyglycidyl ether
(Gly22)-AMyloid b-Protein (1-42)
4-氨基苯甲脒二盐酸盐
卡非佐米杂质PR-059462
(2-Chloro-3,4-difluorophenyl)methanol
6 - 氨甲基-4H-苯并[1,4]恶嗪-3 - 酮盐酸盐